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Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 PubMed Central PMCID: PMC4264672

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PubMed Central PMCID: PMC4264672

mean tumor numbers

CAS Number: 936890-98-1

regulating deubiquitination activity of USP10 and USP13 by Beclin1 provides a mechanism for Beclin1 to control the levels of p53

and an increased escape latency of rats in the Morris water maze test

Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 PubMed Central PMCID: PMC4264672Su 11274, CAS No. 658084 23 2, is a selective Met tyrosine kinase inhibitor with IC50 of 10 nM. Su 11274 increases tumorigenicity and enriched for melanoma initiating cells by bioenergetic modulation. Su 11274 suppresses proliferation and motility of pancreatic cancer cells. Su 11274 enhances the response of the prostate cancer cell line DU145 to ionizing radiation. Su 11274 exhibits a selective inhibition pattern toward different receptor mutated

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